My mom's machine has slowed to a crawl, this morning it took it 20 minutes to boot up. Below is the current HiJackThis Log. Thanks in advance!

Logfile of HijackThis v1.99.1
Scan saved at 3:55:53 PM, on 4/16/2005
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\Common Files\Symantec Shared\ccSetMgr.exe
C:\Program Files\Norton AntiVirus\navapsvc.exe
C:\WINDOWS\system32\atiptaxx.exe
C:\Program Files\Norton AntiVirus\SAVScan.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Common Files\Symantec Shared\ccApp.exe
C:\Program Files\Common Files\Symantec Shared\CCPD-LC\symlcsvc.exe
C:\Program Files\HP\hpcoretech\hpcmpmgr.exe
C:\Program Files\HP\HP Software Update\HPWuSchd2.exe
C:\Program Files\Common Files\Real\Update_OB\realsched.exe
C:\Program Files\Common Files\Symantec Shared\ccEvtMgr.exe
C:\Program Files\MSN Apps\Updater\01.02.3000.1001\en-us\msnappau.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\MSN Messenger\MsnMsgr.Exe
C:\Program Files\Common Files\Symantec Shared\Security Center\SymWSC.exe
C:\Program Files\AWS\WeatherBug\Weather.exe
C:\Program Files\HP\Digital Imaging\bin\hpqtra08.exe
C:\Program Files\MediaKey\Versato.exe
C:\Program Files\SpywareGuard\sgmain.exe
C:\Program Files\SpywareGuard\sgbhp.exe
C:\Program Files\MediaKey\OSD.EXE
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\Outlook Express\msimn.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\PROGRA~1\WINZIP\winzip32.exe
C:\unzipped\hijackthis\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.rr.com/flash/index.cfm
N3 - Netscape 7: user_pref("browser.startup.homepage", "http://home.netscape.com/bookmark/7_1/home.html"); (C:\Documents and Settings\Jean LeBlanc\Application Data\Mozilla\Profiles\default\b6q63fbl.slt\prefs.js)
N3 - Netscape 7: user_pref("browser.search.defaultengine", "engine://C%3A%5CPROGRA%7E1%5CNetscape%5CNetscape%5Csearchplugins%5CSBWeb_01.src"); (C:\Documents and Settings\Jean LeBlanc\Application Data\Mozilla\Profiles\default\b6q63fbl.slt\prefs.js)
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 5.0\Reader\ActiveX\AcroIEHelper.ocx
O2 - BHO: SpywareGuard Download Protection - {4A368E80-174F-4872-96B5-0B27DDD11DB2} - C:\Program Files\SpywareGuard\dlprotect.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: ST - {9394EDE7-C8B5-483E-8773-474BF36AF6E4} - C:\Program Files\MSN Apps\ST\01.02.3000.1002\en-xu\stmain.dll
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - c:\program files\google\googletoolbar1.dll
O2 - BHO: MSNToolBandBHO - {BDBD1DAD-C946-4A17-ADC1-64B5B4FF55D0} - C:\Program Files\MSN Apps\MSN Toolbar\01.02.3000.1001\en-us\msntb.dll
O2 - BHO: NAV Helper - {BDF3E430-B101-42AD-A544-FADC6B084872} - C:\Program Files\Norton AntiVirus\NavShExt.dll
O3 - Toolbar: Norton AntiVirus - {42CDD1BF-3FFB-4238-8AD1-7859DF00B1D6} - C:\Program Files\Norton AntiVirus\NavShExt.dll
O3 - Toolbar: &Google - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - c:\program files\google\googletoolbar1.dll
O3 - Toolbar: MSN - {BDAD1DAD-C946-4A17-ADC1-64B5B4FF55D0} - C:\Program Files\MSN Apps\MSN Toolbar\01.02.3000.1001\en-us\msntb.dll
O4 - HKLM\..\Run: [PCTVOICE] pctspk.exe
O4 - HKLM\..\Run: [HP OfficeJet Series 500] "C:\Program Files\Hewlett-Packard\HP OfficeJet Series 500\bin\ktchnsnk.exe" -reg "Software\Hewlett-Packard\OfficeJet Series 500\Install"
O4 - HKLM\..\Run: [AtiPTA] atiptaxx.exe
O4 - HKLM\..\Run: [ccApp] "C:\Program Files\Common Files\Symantec Shared\ccApp.exe"
O4 - HKLM\..\Run: [HP Component Manager] "C:\Program Files\HP\hpcoretech\hpcmpmgr.exe"
O4 - HKLM\..\Run: [HP Software Update] "C:\Program Files\HP\HP Software Update\HPWuSchd2.exe"
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe" -osboot
O4 - HKLM\..\Run: [Symantec NetDriver Monitor] C:\PROGRA~1\SYMNET~1\SNDMon.exe
O4 - HKLM\..\Run: [msnappau] "C:\Program Files\MSN Apps\Updater\01.02.3000.1001\en-us\msnappau.exe"
O4 - HKLM\..\Run: [MSConfig] C:\WINDOWS\PCHealth\HelpCtr\Binaries\MSConfig.exe /auto
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [msnmsgr] "C:\Program Files\MSN Messenger\MsnMsgr.Exe" /background
O4 - HKCU\..\Run: [Microsoft Works Update Detection] ???\WkDetect.exe
O4 - HKCU\..\Run: [Weather] C:\Program Files\AWS\WeatherBug\Weather.exe 1
O4 - Startup: SpywareGuard.lnk = C:\Program Files\SpywareGuard\sgmain.exe
O4 - Global Startup: HP Digital Imaging Monitor.lnk = C:\Program Files\HP\Digital Imaging\bin\hpqtra08.exe
O4 - Global Startup: MediaKey.lnk = C:\Program Files\MediaKey\Versato.exe
O8 - Extra context menu item: &Google Search - res://c:\program files\google\GoogleToolbar1.dll/cmsearch.html
O8 - Extra context menu item: Backward Links - res://c:\program files\google\GoogleToolbar1.dll/cmbacklinks.html
O8 - Extra context menu item: Cached Snapshot of Page - res://c:\program files\google\GoogleToolbar1.dll/cmcache.html
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~3\OFFICE11\EXCEL.EXE/3000
O8 - Extra context menu item: Similar Pages - res://c:\program files\google\GoogleToolbar1.dll/cmsimilar.html
O8 - Extra context menu item: Translate into English - res://c:\program files\google\GoogleToolbar1.dll/cmtrans.html
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\WINDOWS\System32\msjava.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\WINDOWS\System32\msjava.dll
O9 - Extra button: Messenger - {4528BBE0-4E08-11D5-AD55-00010333D0AD} - C:\Program Files\Yahoo!\Messenger\yhexbmes0521.dll
O9 - Extra 'Tools' menuitem: Yahoo! Messenger - {4528BBE0-4E08-11D5-AD55-00010333D0AD} - C:\Program Files\Yahoo!\Messenger\yhexbmes0521.dll
O9 - Extra button: ICQ Pro - {6224f700-cba3-4071-b251-47cb894244cd} - C:\PROGRA~1\ICQ\ICQ.exe
O9 - Extra 'Tools' menuitem: ICQ - {6224f700-cba3-4071-b251-47cb894244cd} - C:\PROGRA~1\ICQ\ICQ.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra button: WeatherBug - {AF6CABAB-61F9-4f12-A198-B7D41EF1CB52} - C:\PROGRA~1\AWS\WEATHE~1\Weather.exe (HKCU)
O12 - Plugin for .mov: C:\Program Files\Internet Explorer\PLUGINS\npqtplugin.dll
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O12 - Plugin for .tiff: C:\Program Files\Internet Explorer\PLUGINS\npqtplugin3.dll
O16 - DPF: {00B71CFB-6864-4346-A978-C0A14556272C} (Checkers Class) - http://messenger.zone.msn.com/binary/msgrchkr.cab
O16 - DPF: {14B87622-7E19-4EA8-93B3-97215F77A6BC} (MessengerStatsClient Class) - http://messenger.zone.msn.com/binary/Messe...nt.cab28578.cab
O16 - DPF: {2B96D5CC-C5B5-49A5-A69D-CC0A30F9028C} (MiniBugTransporterX Class) - http://download.weatherbug.com/minibug/tri...Transporter.cab?
O16 - DPF: {5F0C30E4-1E72-4DCC-85E5-57810F1CA97B} (McUpdatePortalFactory Class) - https://mysupport.nai.com/amiuptodate/bin/1...pdatePortal.cab
O16 - DPF: {74D05D43-3236-11D4-BDCD-00C04F9A3B61} (HouseCall Control) - http://a840.g.akamai.net/7/840/537/2004061...all/xscan53.cab
O16 - DPF: {77E32299-629F-43C6-AB77-6A1E6D7663F6} (Groove Control) - http://www.nick.com/common/groove/gx/GrooveAX25.cab
O16 - DPF: {8E0D4DE5-3180-4024-A327-4DFAD1796A8D} (MessengerStatsClient Class) - http://messenger.zone.msn.com/binary/Messe...StatsClient.cab
O16 - DPF: {9A9307A0-7DA4-4DAF-B042-5009F29E09E1} (ActiveScan Installer Class) - http://www.pandasoftware.com/activescan/as5/asinst.cab
O16 - DPF: {B8BE5E93-A60C-4D26-A2DC-220313175592} (ZoneIntro Class) - http://messenger.zone.msn.com/binary/ZIntro.cab28578.cab
O16 - DPF: {B9191F79-5613-4C76-AA2A-398534BB8999} (YAddBook Class) - http://us.dl1.yimg.com/download.yahoo.com/...utocomplete.cab
O16 - DPF: {C3DFA998-A486-11D4-AA25-00C04F72DAEB} (MSN Photo Upload Tool) - http://sc.groups.msn.com/controls/PhotoUC/MsnPUpld.cab
O16 - DPF: {DA758BB1-5F89-4465-975F-8D7179A4BCF3} (WheelofFortune Object) - http://messenger.zone.msn.com/binary/WoF.cab28578.cab
O16 - DPF: {DF780F87-FF2B-4DF8-92D0-73DB16A1543A} (PopCapLoader Object) - http://www.popcap.com/games/popcaploader_v6.cab
O16 - DPF: {EF791A6B-FC12-4C68-99EF-FB9E207A39E6} (McFreeScan Class) - http://download.mcafee.com/molbin/iss-loc/...311/mcfscan.cab
O16 - DPF: {EF99BD32-C1FB-11D2-892F-0090271D4F88} - http://us.dl1.yimg.com/download.yahoo.com/...bio4_0_2_10.cab
O16 - DPF: {F04A8AE2-A59D-11D2-8792-00C04F8EF29D} (Hotmail Attachments Control) - http://lw8fd.law8.hotmail.msn.com/activex/HMAtchmt.ocx
O16 - DPF: {F58E1CEF-A068-4C15-BA5E-587CAF3EE8C6} (MSN Chat Control 4.5) - http://chat.msn.com/bin/msnchat45.cab
O23 - Service: Ati HotKey Poller - Unknown owner - C:\WINDOWS\System32\Ati2evxx.exe
O23 - Service: Symantec Event Manager (ccEvtMgr) - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\ccEvtMgr.exe
O23 - Service: Symantec Password Validation (ccPwdSvc) - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\ccPwdSvc.exe
O23 - Service: Symantec Settings Manager (ccSetMgr) - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\ccSetMgr.exe
O23 - Service: Norton AntiVirus Auto Protect Service (navapsvc) - Symantec Corporation - C:\Program Files\Norton AntiVirus\navapsvc.exe
O23 - Service: Pml Driver HPZ12 - HP - C:\WINDOWS\System32\HPZipm12.exe
O23 - Service: SAVScan - Symantec Corporation - C:\Program Files\Norton AntiVirus\SAVScan.exe
O23 - Service: ScriptBlocking Service (SBService) - Symantec Corporation - C:\PROGRA~1\COMMON~1\SYMANT~1\SCRIPT~1\SBServ.exe
O23 - Service: Symantec Network Drivers Service (SNDSrvc) - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\SNDSrvc.exe
O23 - Service: Symantec Core LC - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\CCPD-LC\symlcsvc.exe
O23 - Service: SymWMI Service (SymWSC) - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\Security Center\SymWSC.exe

Your log is clean. There is nothing obvious showing.

First:
Download and install the disk cleanup utility called Cleanup!
Links:
http://cleanup.stevengould.org/
http://www.hijackthislogs.com/dl/CleanUp312.exe

Cleanup! will get rid of any malware which may be hiding in your temp folders ( a common hiding place). You may also regain a massive amount of disk space.

Here is a tutorial which describes its usage:
http://www.bleepingcomputer.com/forums/tutorial93.html


Run the disk cleanup utility called Cleanup! that you have already downloaded and installed

Check the custom settings to your liking under options, but be sure to delete temporary files and temporary internet files for all user profiles. Also, cleanout the prefetch folder and the recycle bin.

Then reboot into normal mode to let it clean out the remaining files.


Second:
Would you please use HiJackThis to produces startup list and post it here:
1. From HJT main screen, click 'Config' button
2. Click 'Misc Tools' button
3. Check both boxes to the right of 'Generate StartupList Log' button
4. Click 'Generate StartupList Log' button
5. Click 'Yes' in the next dialog
6. Save the log and post a copy in this thread.